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FASTA & Protein Processing

Parse FASTA files, digest proteins, and map peptides.

parse_uniprot_fasta()
Read UniProt protein sequences from FASTA.
rank_uniprot_entries()
Assign rank to UniProt entries
proteins_digest()
In silico protein digestion
map_peptides_to_proteins()
Map peptide sequence IDs to proteins using a FASTA file

Protein Group Assembly

Infer protein groups from peptide-to-protein mappings.

assemble_protein_groups()
Assemble protein groups from peptide-to-protein mapping
append_protein_groups_info()
Append extra information to a protein groups frame
default_protein_grouping()
Functions for protein group inference, inspired by the concepts from "MaxQuant's post-computational razor: a massively parallel graphical model for post-processing proteomics data" by K. S. Rudolph et al.
pregrouped_protein_grouping()
Rule for merging proteins that allows for pre-grouping

Visualization

Seer-branded ggplot2 themes and color scales.

theme_seer()
Seer ggplot2 Theme
seer_palette
Seer Color Palette
scale_colour_seer() scale_color_seer()
Seer Color Scale for ggplot2
scale_fill_seer()
Seer Fill Scale for ggplot2

Data Display

Helpers for readable data frame output.

printable()
Prepares a data frame for printing by selecting columns and applying specific transformations.

Code Style

Seer coding style guide for styler.

seer_style()
Seer Styler Guide

Reference Data

Built-in datasets.

plasma_markers_geyer
Plasma Proteins Biomarkers